绵、山羊毛囊发育与毛发弯曲机制研究进展

doi:10.11843/j.issn.0366-6964.2018.08.001

Abstract

Abstract:

As the only micro organ, the hair follicles grow periodically throughout life, hair follicle is in a relatively active growing and metabolic state. Hair shaft is a sustained developing structure that consists of hair follicle's terminally differentiated cells. The morphological change of hair shaft depends on the structural development of hair follicle, since mitosis, proliferation and differentiation of hair follicle stem cells determine the growth of hair fibre. In recent years, thanks to the improvement and innovation of research methods, great progresses have been made rapidly on studies of hair curvature at the molecular genetics level, and some genetic factors and signal pathways have been uncovered and verified, which act on hair follicle development and hair wave patterns. We introduced the anatomical and morphogenetic properties of hair follicle, and then generalized research advances of hair curvature on the basis of hair follicle's different cell layers and their specific regulatory genes; finally, we also described an interaction network among the canonical pathways and genes related to hair follicle development. The review was presented in order to provide references for the study on molecular mechanisms of wool curling in a dynamic morphogeny.

CLC Number:

S813.1

XIAO Ping, ZHONG Tao, LIU Zhan-fa, PU Ya-bin, MA Yue-hui, ZHAO Qian-jun. Research Progress of Mechanism of Hair Follicle Development and Hair Curvature in Sheep and Goat[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2018, 49(8): 1567-1576.

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Research Progress of Mechanism of Hair Follicle Development and Hair Curvature in Sheep and Goat

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